Process for preparing 1-pyruvyl-L-proline

Preparation of 1-pyruvyl-L-proline (I) comprises reacting L-proline with glucuronic acid methyl ester-dimethylketal in the presence of alkali metal alkoxides in organic solvent and subsequent acid hydrolysis of the resulting ketal. (I) is isolated by extraction with an organic solvent.

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Hauptverfasser: CURT ZIMMERMANN, KARLHEINZ GISELBRECHT
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KARLHEINZ GISELBRECHT
description Preparation of 1-pyruvyl-L-proline (I) comprises reacting L-proline with glucuronic acid methyl ester-dimethylketal in the presence of alkali metal alkoxides in organic solvent and subsequent acid hydrolysis of the resulting ketal. (I) is isolated by extraction with an organic solvent.
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subjects APPARATUS THEREFOR
CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
THEIR RELEVANT APPARATUS
TRANSPORTING
title Process for preparing 1-pyruvyl-L-proline
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