Process for preparing 1-pyruvyl-L-proline

Preparation of 1-pyruvyl-L-proline (I) comprises reacting L-proline with glucuronic acid methyl ester-dimethylketal in the presence of alkali metal alkoxides in organic solvent and subsequent acid hydrolysis of the resulting ketal. (I) is isolated by extraction with an organic solvent.

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Bibliographische Detailangaben
Hauptverfasser:	CURT ZIMMERMANN, KARLHEINZ GISELBRECHT
Format:	Patent
Sprache:	eng
Schlagworte:	APPARATUS THEREFOR CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL THEIR RELEVANT APPARATUS TRANSPORTING
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Beschreibung
Zusammenfassung:	Preparation of 1-pyruvyl-L-proline (I) comprises reacting L-proline with glucuronic acid methyl ester-dimethylketal in the presence of alkali metal alkoxides in organic solvent and subsequent acid hydrolysis of the resulting ketal. (I) is isolated by extraction with an organic solvent.