Benzothia(oxa)diazol derivatives and their use as endothelin-receptor antagonists

Novel compounds of the formula Iin whichR isX is O or S,andR1, R2, R3, R4, R5 and R6 have the meaning indicated in patent claim 1,or a tautomeric ring-closed form, and the (E) isomers and their saltsexhibit endothelin receptor-antagonistic properties.

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Bibliographische Detailangaben
Hauptverfasser:	WERNER MEDERSKI, CLAUS JOCHEN SCHMITGES, CLAUDIA WILM, MARIA CHRISTADLER, DIETER DORSCH, MATHIAS OSSWALD
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Novel compounds of the formula Iin whichR isX is O or S,andR1, R2, R3, R4, R5 and R6 have the meaning indicated in patent claim 1,or a tautomeric ring-closed form, and the (E) isomers and their saltsexhibit endothelin receptor-antagonistic properties.