17-DISUBSTITUTED-ANDROST-4-EN-3-ONE DERIVATIVES

17-DISUBSTITUTED-ANDROST-4-EN-3-ONE DERIVATIVES

Novel anti-inflammatory agents based on a glucocortico-steroid structure having a general formula I the groups R1 to R5, and Z being defined; X is O or S. One example is based on the inactive metabolite cortienic acid which is activated by the introduction of non-toxic substituents at positions 17 a...

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Bibliographische Detailangaben
1. Verfasser: N.S. BODOR
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
STEROIDS
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Beschreibung
Zusammenfassung:Novel anti-inflammatory agents based on a glucocortico-steroid structure having a general formula I the groups R1 to R5, and Z being defined; X is O or S. One example is based on the inactive metabolite cortienic acid which is activated by the introduction of non-toxic substituents at positions 17 alpha - and 17 beta -.