DNA diagnostics based on mass spectrometry

The invention provides fast and highly accurate mass spectrometer based processes for detecting a particular nucleic acid sequence in a biological sample. Depending on the sequence to be detected, the processes can be used, for example, to diagnose a genetic disease or chromosomal abnormality; a pre...

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Bibliographische Detailangaben
Hauptverfasser: KAI TANG, CHRISTIAN JURINKE, DANIEL P. LITTLE, DONG-JING FU, HUBERT KOSTER, CARSTEN W. SIEGIRT, G. SCOTT HIGGINS, BRIGITTE DARNHOFER-DEMAR, ANDREAS BRAUN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides fast and highly accurate mass spectrometer based processes for detecting a particular nucleic acid sequence in a biological sample. Depending on the sequence to be detected, the processes can be used, for example, to diagnose a genetic disease or chromosomal abnormality; a predisposition to a disease or condition, infection by a pathogenic organism, or for determining identity or heredity.