Cytotoxic compounds: derivatives of the pyrido{2,3,4-(kl)} acridine ring system

Compounds of formula (I), wherein X is selected from the group consisting of O, and NR , where R represents a lower alkyl group; Y is selected from the group consisting of CH and N; R and R are independently selected from the group consisting of NH2, NHR and NR 2, where R and R each represent a lowe...

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Hauptverfasser: DOLORES GARCIA-GRAVALOS, JOSE CARLOS MENENDEZ RAMOS, CARMEN AVENDAIO LOPEZ, MARIA DEL MAR BLANCO CASTRO
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creator DOLORES GARCIA-GRAVALOS
JOSE CARLOS MENENDEZ RAMOS
CARMEN AVENDAIO LOPEZ
MARIA DEL MAR BLANCO CASTRO
description Compounds of formula (I), wherein X is selected from the group consisting of O, and NR , where R represents a lower alkyl group; Y is selected from the group consisting of CH and N; R and R are independently selected from the group consisting of NH2, NHR and NR 2, where R and R each represent a lower alkyl group, or R and R together represent a cycle selected from (a), (b) and (c), wherein R , R and R are independently selected from the group consisting of hydrogen atoms, lower alkyl groups, hydroxy groups and lower alkoxy groups; and Z is selected from the group consisting of O.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Cytotoxic compounds: derivatives of the pyrido{2,3,4-(kl)} acridine ring system
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