Cytotoxic compounds: derivatives of the pyrido{2,3,4-(kl)} acridine ring system
Compounds of formula (I), wherein X is selected from the group consisting of O, and NR , where R represents a lower alkyl group; Y is selected from the group consisting of CH and N; R and R are independently selected from the group consisting of NH2, NHR and NR 2, where R and R each represent a lowe...
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creator | DOLORES GARCIA-GRAVALOS JOSE CARLOS MENENDEZ RAMOS CARMEN AVENDAIO LOPEZ MARIA DEL MAR BLANCO CASTRO |
description | Compounds of formula (I), wherein X is selected from the group consisting of O, and NR , where R represents a lower alkyl group; Y is selected from the group consisting of CH and N; R and R are independently selected from the group consisting of NH2, NHR and NR 2, where R and R each represent a lower alkyl group, or R and R together represent a cycle selected from (a), (b) and (c), wherein R , R and R are independently selected from the group consisting of hydrogen atoms, lower alkyl groups, hydroxy groups and lower alkoxy groups; and Z is selected from the group consisting of O. |
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Y is selected from the group consisting of CH and N; R and R are independently selected from the group consisting of NH2, NHR and NR 2, where R and R each represent a lower alkyl group, or R and R together represent a cycle selected from (a), (b) and (c), wherein R , R and R are independently selected from the group consisting of hydrogen atoms, lower alkyl groups, hydroxy groups and lower alkoxy groups; and Z is selected from the group consisting of O.</description><edition>6</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1998</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19981124&DB=EPODOC&CC=AU&NR=7220898A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19981124&DB=EPODOC&CC=AU&NR=7220898A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DOLORES GARCIA-GRAVALOS</creatorcontrib><creatorcontrib>JOSE CARLOS MENENDEZ RAMOS</creatorcontrib><creatorcontrib>CARMEN AVENDAIO LOPEZ</creatorcontrib><creatorcontrib>MARIA DEL MAR BLANCO CASTRO</creatorcontrib><title>Cytotoxic compounds: derivatives of the pyrido{2,3,4-(kl)} acridine ring system</title><description>Compounds of formula (I), wherein X is selected from the group consisting of O, and NR , where R represents a lower alkyl group; Y is selected from the group consisting of CH and N; R and R are independently selected from the group consisting of NH2, NHR and NR 2, where R and R each represent a lower alkyl group, or R and R together represent a cycle selected from (a), (b) and (c), wherein R , R and R are independently selected from the group consisting of hydrogen atoms, lower alkyl groups, hydroxy groups and lower alkoxy groups; and Z is selected from the group consisting of O.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1998</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPB3rizJL8mvyExWSM7PLcgvzUsptlJISS3KLEssySxLLVbIT1MoyUhVKKgsykzJrzbSMdYx0dXIztGsVUhMBgpl5qUqFGXmpSsUVxaXpObyMLCmJeYUp_JCaW4GeTfXEGcP3dSC_PjU4oLE5NS81JJ4x1BzIyMDC0sLR2PCKgBD8jWB</recordid><startdate>19981124</startdate><enddate>19981124</enddate><creator>DOLORES GARCIA-GRAVALOS</creator><creator>JOSE CARLOS MENENDEZ RAMOS</creator><creator>CARMEN AVENDAIO LOPEZ</creator><creator>MARIA DEL MAR BLANCO CASTRO</creator><scope>EVB</scope></search><sort><creationdate>19981124</creationdate><title>Cytotoxic compounds: derivatives of the pyrido{2,3,4-(kl)} acridine ring system</title><author>DOLORES GARCIA-GRAVALOS ; JOSE CARLOS MENENDEZ RAMOS ; CARMEN AVENDAIO LOPEZ ; MARIA DEL MAR BLANCO CASTRO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_AU7220898A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1998</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>DOLORES GARCIA-GRAVALOS</creatorcontrib><creatorcontrib>JOSE CARLOS MENENDEZ RAMOS</creatorcontrib><creatorcontrib>CARMEN AVENDAIO LOPEZ</creatorcontrib><creatorcontrib>MARIA DEL MAR BLANCO CASTRO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DOLORES GARCIA-GRAVALOS</au><au>JOSE CARLOS MENENDEZ RAMOS</au><au>CARMEN AVENDAIO LOPEZ</au><au>MARIA DEL MAR BLANCO CASTRO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Cytotoxic compounds: derivatives of the pyrido{2,3,4-(kl)} acridine ring system</title><date>1998-11-24</date><risdate>1998</risdate><abstract>Compounds of formula (I), wherein X is selected from the group consisting of O, and NR , where R represents a lower alkyl group; Y is selected from the group consisting of CH and N; R and R are independently selected from the group consisting of NH2, NHR and NR 2, where R and R each represent a lower alkyl group, or R and R together represent a cycle selected from (a), (b) and (c), wherein R , R and R are independently selected from the group consisting of hydrogen atoms, lower alkyl groups, hydroxy groups and lower alkoxy groups; and Z is selected from the group consisting of O.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | Cytotoxic compounds: derivatives of the pyrido{2,3,4-(kl)} acridine ring system |
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