Cytotoxic compounds: derivatives of the pyrido{2,3,4-(kl)} acridine ring system

Compounds of formula (I), wherein X is selected from the group consisting of O, and NR , where R represents a lower alkyl group; Y is selected from the group consisting of CH and N; R and R are independently selected from the group consisting of NH2, NHR and NR 2, where R and R each represent a lowe...

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Hauptverfasser:	DOLORES GARCIA-GRAVALOS, JOSE CARLOS MENENDEZ RAMOS, CARMEN AVENDAIO LOPEZ, MARIA DEL MAR BLANCO CASTRO
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Compounds of formula (I), wherein X is selected from the group consisting of O, and NR , where R represents a lower alkyl group; Y is selected from the group consisting of CH and N; R and R are independently selected from the group consisting of NH2, NHR and NR 2, where R and R each represent a lower alkyl group, or R and R together represent a cycle selected from (a), (b) and (c), wherein R , R and R are independently selected from the group consisting of hydrogen atoms, lower alkyl groups, hydroxy groups and lower alkoxy groups; and Z is selected from the group consisting of O.