Multifunctional reagent for erythrocytes

Multifunctional reagent (A) for erythrocytes (RBC) contains: (i) enough of a carbamate (I) to lyse RBC or to cause their spherization, so that they can be determined by a cytometer or automated counter or; (ii) an agent (II) that induces formation of a carbamate, associated with absorption of carbon...

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Bibliographische Detailangaben
Hauptverfasser:	JEAN-PIERRE DAZIANO, ANDRE VAN AGTHOVEN, JOHN ALLEN MAPLES
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING
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Beschreibung
Zusammenfassung:	Multifunctional reagent (A) for erythrocytes (RBC) contains: (i) enough of a carbamate (I) to lyse RBC or to cause their spherization, so that they can be determined by a cytometer or automated counter or; (ii) an agent (II) that induces formation of a carbamate, associated with absorption of carbon dioxide by RBC, from carbonate and a nitrogen heterocycle or ammonium ion. Independent claims are also included for the following: (1) carbamates of pyrrolidine, morpholine and piperidine; (2) lysis or spherization of RBC in anticoagulant-treated whole blood by treating with (1); (3) preparing leucocytes (WBC) involving lysis of RBC with (1).