Contrast media

The invention relates to MR contrast media containing composite nanoparticles, preferably comprising a superparamagnetic iron oxide core provided with a coating comprising an oxidatively cleaved starch coating optionally together with a functionalized polyalkyleneoxide which serves to prolong blood...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	ROBERT ALAN SNOW, VINAY DESAI, MARSHALL BEEBER, CHRISTOPHER BLACK, BARBARA YUAN, KENNETH KELLAR, GEORGE NA, BRIAN WEEKLEY, DAVID LEE LADD, JASBIR SINGH, ANNE NAEVESTAD, DENNIS KIYOSHI FUJII, JACK STEVENS, JENNIFER WELLONS, TORGRIM ENGELL, WOLFGANG GUNTHER, MICHEL GACEK, EDWARD RICHARD BACON, ANNE KJERSTI FAHLVIK, GREGORY LYNN MCINTIRE
Format:	Patent
Sprache:	eng
Schlagworte:	AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS OF MACROMOLECULAR COMPOUNDS COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSESC01D OR C01F GENERAL PROCESSES OF COMPOUNDING HUMAN NECESSITIES HYGIENE INORGANIC CHEMISTRY MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC MACROMOLECULAR COMPOUNDS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES THEIR PREPARATION OR CHEMICAL WORKING-UP WORKING-UP
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Beschreibung
Zusammenfassung:	The invention relates to MR contrast media containing composite nanoparticles, preferably comprising a superparamagnetic iron oxide core provided with a coating comprising an oxidatively cleaved starch coating optionally together with a functionalized polyalkyleneoxide which serves to prolong blood residence.