Recombinant attentuated canarypox ALVAC virus expression vectors containing heterologous DNA segments encoding malarial gene products

What is described is a recombinant poxvirus, such as vaccinia or canarypox virus, containing foreign DNA from Plasmodium. What is also described is a vaccine containing the recombinant poxvirus for inducing an immunological response in a host animal inoculated with the vaccine. Preferred recombinant...

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Bibliographische Detailangaben
Hauptverfasser: ENZO PAOLETTI, CHARLES DE TAISNE, JOHN A TINE
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:What is described is a recombinant poxvirus, such as vaccinia or canarypox virus, containing foreign DNA from Plasmodium. What is also described is a vaccine containing the recombinant poxvirus for inducing an immunological response in a host animal inoculated with the vaccine. Preferred recombinants have attenuated virulence.