Detection of dna damaging agents

The present invention relates to a recombinant DNA molecule comprising a regulatory element associated in nature with the regulation of the expression of DNA repair proteins (e.g. an RNR regulatory element) operatively linked to a DNA sequence that encodes a light emitting reporter protein and also...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	RICHARD MAURICE WALMSLEY, WOLF DIETRICH HEYER
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a recombinant DNA molecule comprising a regulatory element associated in nature with the regulation of the expression of DNA repair proteins (e.g. an RNR regulatory element) operatively linked to a DNA sequence that encodes a light emitting reporter protein and also vectors and cells comprising such DNA molecules. The invention further relates to improved genotoxic tests that utilise such DNA molecules.