Transgenic pathogen-resistant organism
New transgenic, pathogen-resistant organisms have a genome contg. at least 2 different genes, under control of active promoters, with pathogen-inhibiting activity. Also new are DNA transfer vectors contg. inserted DNA sequences for prepn. of such organisms. Partic. the genes (of fungal, bacterial, a...
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Zusammenfassung: | New transgenic, pathogen-resistant organisms have a genome contg. at least 2 different genes, under control of active promoters, with pathogen-inhibiting activity. Also new are DNA transfer vectors contg. inserted DNA sequences for prepn. of such organisms. Partic. the genes (of fungal, bacterial, animal, plant or viral origin) encode products that reduce the viability of fungi, esp. chitinase; glucanase; protein-synthesis inhibitor (PSI) or antifungal protein (AFP). The transgenic organism is pref. a plant, esp. tobacco, potato, strawberry, maize, rape or tomato. The specification includes nucleic acid and amino acid sequences for AFP of Aspergilllus giganteus (275 bp); PSI of Hordeum vulgare (1079 bp); exo-chitinase (ChiS) of Serratia marcescens (2329 bp); chitinase G of H. vulgare (1013 bp), and glucanase of H. vulgare (1249 bp). |
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