B LACTAM SULPHONIC ACIDS

Beta lactams (I) having an SO3M substit. at 1-position and an opt. substd. or protected amino gp. or azido gp. at the 3-position are new. (M is hydrogen or a cation). They can also be substd. at the 4-position by alkyl, cycloalkyl, opt. substd. phenyl, alkoxycarbonyl, alken-1-yl, alkyn-1-yl, 2-pheny...

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1. Verfasser: R.B. SYKES
Format: Patent
Sprache:eng
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Zusammenfassung:Beta lactams (I) having an SO3M substit. at 1-position and an opt. substd. or protected amino gp. or azido gp. at the 3-position are new. (M is hydrogen or a cation). They can also be substd. at the 4-position by alkyl, cycloalkyl, opt. substd. phenyl, alkoxycarbonyl, alken-1-yl, alkyn-1-yl, 2-phenylethenyl or 2-phenylethynyl. (I) having a 3-acylamino substit. are antibacterials effective against Gram negative and positive species, and useful therapeutically in human or veterinary medicine. The other new cpds. are intermediates.