Novel c-19-halogen-substituted steroids of the androst-9(11)-ene-series, methodsfor the production and use thereof

The invention relates to new C-19-halogen-substituted steroids of the androst-9(11)-ene series, namely 17beta-hydroxy-19-halogen-androsta-4,9(11)-dien-3-ones of general formula (I) and process for their production. In addition, the use of new radiohalogen-labeled compounds of Formula (I) as radiopha...

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Bibliographische Detailangaben
Hauptverfasser:	ROLAND GOLDE, KARL-HEINRICH FRITZEMEIER, GUNTER NEEF
Format:	Patent
Sprache:	eng
Schlagworte:	APPARATUS THEREFOR CHEMISTRY GENERAL METHODS OF ORGANIC CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS STEROIDS
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Beschreibung
Zusammenfassung:	The invention relates to new C-19-halogen-substituted steroids of the androst-9(11)-ene series, namely 17beta-hydroxy-19-halogen-androsta-4,9(11)-dien-3-ones of general formula (I) and process for their production. In addition, the use of new radiohalogen-labeled compounds of Formula (I) as radiopharmeceutical agents is the subject of the invention as well as the use of non-labeled compounds of Formula (I) as starting products for the production of new biologically active 5beta-substituted androst-9(11)-enes of general formula (II) and the new 6beta,19-cycloandrostadienes of Formula (III) as well as processes for their production and their use.