Soluble salts of 4-amino-2(4,4-dimethylimidazolidin-2-on-1- yl)pyrimidine-5-carboxylic acid N-methyl-N-(3-trifluoromethyl-phenyl)amide, a process for thepreparation thereof, the use thereof as pharmaceuticals and starting materials

Soluble salts of 4-amino-2(4,4-dimethylimidazolidin-2-on-1- yl)pyrimidine-5-carboxylic acid N-methyl-N-(3-trifluoromethyl-phenyl)amide, a process for thepreparation thereof, the use thereof as pharmaceuticals and starting materials

Water-soluble and easily soluble salts of 4-amino-2-(4,4-dimethyl-imidazolin-2-on-1-yl)-pyrimidine-5-carboxylic acid N-methyl-N-(3-trifluoromethyl-phenyl)-amide and a process for their preparation. The compounds are suitable for treatment of lipid metabolism disturbances which are favourably influen...

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Bibliographische Detailangaben
Hauptverfasser: ERNOLD GRANZER, KLAUS-DIETER KAMPE, MANFRED HUTTINGER, MICHAEL LEINEWEBER
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Water-soluble and easily soluble salts of 4-amino-2-(4,4-dimethyl-imidazolin-2-on-1-yl)-pyrimidine-5-carboxylic acid N-methyl-N-(3-trifluoromethyl-phenyl)-amide and a process for their preparation. The compounds are suitable for treatment of lipid metabolism disturbances which are favourably influenced by stimulating the hepatic LDL-receptor. The compounds of the formula IV and their salts are also described.