Oral preparation for release in lower digestive tracts

An oral preparation for release in lower digestive tracts, prepared by filling a hard capsule made from a base mainly comprising chitosan with a solid preparation containing a principal agent and a solid organic acid which, in a dissolved state, can dissolve chitosan and forming an enteric coating o...

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Bibliographische Detailangaben
Hauptverfasser: NAOKI UCHIDA, AKIYA YAMADA, SHIGEYUKI TAKAMA, YUKIKO INAMOTO, MISUZU KADORIKU, TAKAHIKO WATO
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:An oral preparation for release in lower digestive tracts, prepared by filling a hard capsule made from a base mainly comprising chitosan with a solid preparation containing a principal agent and a solid organic acid which, in a dissolved state, can dissolve chitosan and forming an enteric coating on the surface of the capsule. The preparation enables any desired release time to be set without being affected by the pH by virtue of the water-permeability due to the porousness of the chitosan.