N sulfonyl aminoacid derivatives as inhibitors of metalloproteinase

The present invention provides a matrix metalloproteinase inhibiting compound having the structure (I), or a salt, an enantiomer, a diastereomer, a racemate, or a tautomer thereof. In other embodiments, the present invention provides a method of changing the conformation of a matrix metalloproteinas...

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Bibliographische Detailangaben
Hauptverfasser: SUSAN C. HOWARD, WILLIAM C. STALLINGS, HUEY S. SHIEH, GARY A. DE CRECENZO, JOSEPH J MCDONALD
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides a matrix metalloproteinase inhibiting compound having the structure (I), or a salt, an enantiomer, a diastereomer, a racemate, or a tautomer thereof. In other embodiments, the present invention provides a method of changing the conformation of a matrix metalloproteinase, a method of inhibiting a matrix metalloproteinase, and a method of treating osteoarthritis.