Pyridine compounds, intermediates, processes, compositions, and methods

The present invention is directed to compounds of formula (I) wherein n is 2 or 3; R is dimethylamino, diethylamino, 1-piperidinyl, 1-pyrrolidinyl, 4-morpholinyl, or 1-hexamethyleneimino; R is hydrogen, loweralkyl of C1-C4, phenyl, or mono- or di-substituted phenyl wherein each substituent is independently halo, methyl, hydroxy, C1-C6-alkoxy, benzyloxy, C1-C6-alkanoyloxy, benzoyloxy, substituted benzoyloxy bearing 1 to 3 substituents each of which is independently halo, C1-C4-loweralkyl, or C1-C4-loweralkoxy, C1-C5-alkoxycarbonyloxy or C4-C6-alkylsulfonyloxy; R is hydrogen, hydroxy, C1-C6-alkoxy, benzyloxy, C1-C6-alkanoyloxy, benzoyloxy, substituted benzoyloxy bearing 1 to 3 substituents each of which is independently halo, C1-C4-loweralkyl, or C1-C4-loweralkoxy, C1-C5-alkoxycarbonyloxy, or C4-C6-alkylsulfonyloxy; and the pharmaceutically acceptable acid addition salts, which are for the treatment of post menopausal symptoms such as osteoporosis, cardiovascular conditions such as hyperlipidaemia, and the like.