A new 5H-benzodiazepine derivative, pharmaceutical compositions containing same and process for preparing them

The invention relates to the new 1-(3-chlorophenyl)-4-hydroxymethyl-7,8-dimethoxy-5H-2,3-benzodiazepine of formula (I) (I) and pharmaceutically acceptable acid addition salts thereof, furthermore to a process for preparing these compounds. The compounds according to the invention possess valuable an...

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Bibliographische Detailangaben
Hauptverfasser:	GABOR ZOLYOMI, MARTA RUSZ, FERENC ANDRASI, TAMAS HAMORI, PETER BOTKA, EVA TOMORI, JENO KOROSI, IMRE MORAVCSIK, GYULA HORVATH, KATALIN GOLDSCHMIDT
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to the new 1-(3-chlorophenyl)-4-hydroxymethyl-7,8-dimethoxy-5H-2,3-benzodiazepine of formula (I) (I) and pharmaceutically acceptable acid addition salts thereof, furthermore to a process for preparing these compounds. The compounds according to the invention possess valuable anxiolytic, antiaggressive and antidepressant effects and have at the same time favorable acute toxicity values, so they can be used to advantage in therapy.