Enhanced bioavailability pharmaceutical composition containing probucol

A pharmaceutical composition of probucol that both enhances bioavailability of the drug and reduces plasma drug level variability in a patient population comprising a therapeutically effective amount of probucol dissolved in a propylene glycol ester of fatty acids wherein the fatty acids are selecte...

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Bibliographische Detailangaben
Hauptverfasser: PHADKE S DEEPAK, MELISSA P. NEDDERMEYER, KENNETH G BASSLER
Format: Patent
Sprache:eng
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Zusammenfassung:A pharmaceutical composition of probucol that both enhances bioavailability of the drug and reduces plasma drug level variability in a patient population comprising a therapeutically effective amount of probucol dissolved in a propylene glycol ester of fatty acids wherein the fatty acids are selected from the group consisting of the fatty acids represented by CxH2xO2, wherein x is 4, 6, 8, 10, 12, 14, 16.