PENTAPEPTIDE HAVING SPECIFIC INHIBITING EFFECT ON EPIDERMAL CELL PROLIFERATION, THE SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AND A PROCESS FOR THE PREPARATION OF THE PENTAPEPTIDE AND THE PHARMACEUTICAL COMPOSITIONS

PENTAPEPTIDE HAVING SPECIFIC INHIBITING EFFECT ON EPIDERMAL CELL PROLIFERATION, THE SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AND A PROCESS FOR THE PREPARATION OF THE PENTAPEPTIDE AND THE PHARMACEUTICAL COMPOSITIONS

The present invention relates to novel pentapeptide of formula pAad-Glu-Asp-Ser-Gly-OH, wherein pAad represents the acyl group of pyro-alpha-aminoadipic acid, and salts thereof having specific inhibiting effect on epidermal cell proliferation, and pharmaceutical compositions comprising the same. The...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: TAMAS SZIRTES, LAJOS KISFALUDY, ANDRAS BALAZS, ISTVAN SCHON
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to novel pentapeptide of formula pAad-Glu-Asp-Ser-Gly-OH, wherein pAad represents the acyl group of pyro-alpha-aminoadipic acid, and salts thereof having specific inhibiting effect on epidermal cell proliferation, and pharmaceutical compositions comprising the same. The invention also relates to a process for the preparation of both the pentapeptide and the pharmaceutical composition.