Substituted (hetero)aryl carboxamide derivatives as microsomal triglyceride transfer protein (mtp) and apolipoprotein b (apo b) secretion

Substituted (hetero)aryl carboxamide derivatives as microsomal triglyceride transfer protein (mtp) and apolipoprotein b (apo b) secretion

Compounds of formula (I) wherein R1, L, L', alk, W and Z have the meanings as defined hereinbefore; and pharmaceutically acceptable salts thereof; are useful as inhibitors of microcosmal triglyceride transfer protein (MTP) and of apolipoprotein B (apo B) secretion.

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Bibliographische Detailangaben
1. Verfasser: ROBERT, E. DAMON II
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Compounds of formula (I) wherein R1, L, L', alk, W and Z have the meanings as defined hereinbefore; and pharmaceutically acceptable salts thereof; are useful as inhibitors of microcosmal triglyceride transfer protein (MTP) and of apolipoprotein B (apo B) secretion.