VACCINE AGAINST BOVINE LEUKEMIA VIRUS

The vaccine against bovine leukemia virus (BLV) contains a peptide fraction, or a recombinant virus which express it, which includes the envelope glycoprotein gp51 of BLV virus and which leads to a high degree of neutralizing antibody formation. The gp51 glycoprotein is associated with a transmembra...

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Hauptverfasser: DANIEL GEORGES JOSEPH GHISLAIN PORTETELLE, ARSENE LEON GHISLAIN BURNY, VERONIQUE JOSETTE JACQUELINE MARIE VONECHE
Format: Patent
Sprache:eng
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Zusammenfassung:The vaccine against bovine leukemia virus (BLV) contains a peptide fraction, or a recombinant virus which express it, which includes the envelope glycoprotein gp51 of BLV virus and which leads to a high degree of neutralizing antibody formation. The gp51 glycoprotein is associated with a transmembrane glycoprotein or a specific monoclonal antibody of one of the epitopes of gp51, so that the gp51 glycoprotein is restored to its native configuration in which epitopes F, G and H are present, these epitopes being responsible for the biological activity of BLV virus, in a pharmaceutical vehicle or excipient such as those which are used to constitute vaccines.