GENETICALLY ATTENUATED BACTERIA

A vaccine composition comprising a genetically-attenuated bacterial strain which contains at least two mutations of the same pheno-type which strain is rendered avirulent while retaining immunogenicity, together with an inert, immunologically-acceptable carrier.

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Bibliographische Detailangaben
Hauptverfasser: A.M. HOOKE, M.P. OESCHGER, J.A. BELLANTI
Format: Patent
Sprache:eng
Schlagworte:
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Beschreibung
Zusammenfassung:A vaccine composition comprising a genetically-attenuated bacterial strain which contains at least two mutations of the same pheno-type which strain is rendered avirulent while retaining immunogenicity, together with an inert, immunologically-acceptable carrier.