OCTAHYDROTHIAZOLO 4,5-G QUNOLINES

Trans-(±)-2,5-optionally substituted-octahydrothiazolo [4,5-g]quinolines, or their enantiomers, or their pharmaceutically-acceptable acid addition or quaternary salts thereof, are useful as dopamine agonists. They have the formulawhereinR is H, benzyl, methyl, ethyl, n-propyl or allyl;R1is H, OH, ha...

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Bibliographische Detailangaben
Hauptverfasser: ROBERT DANIEL TITUS, EDMUND CARL KORNFELD
Format: Patent
Sprache:eng
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Zusammenfassung:Trans-(±)-2,5-optionally substituted-octahydrothiazolo [4,5-g]quinolines, or their enantiomers, or their pharmaceutically-acceptable acid addition or quaternary salts thereof, are useful as dopamine agonists. They have the formulawhereinR is H, benzyl, methyl, ethyl, n-propyl or allyl;R1is H, OH, halogen, methyl, HN2, NHC1-3 alkyl, N(C1-3 alkyl)2, 1-pyrrolidinyl, NHCOC1-3 alkyl, or NHC1-2 alkylphenyl; ora pharmaceutically-acceptable acid addition salt thereof.