ALLYLOXY- AND ALLYLTHIO-2,3,4,5 TETRAHYDRO 1H-3-BENZAZEPINES

ALLYLOXY- AND ALLYLTHIO-2,3,4,5 TETRAHYDRO 1H-3-BENZAZEPINES

Compounds of the structural formula: in which: R is hydrogen or a lower alkyl of 1-6 carbons; and R , R and R are allyloxy, allylthio, halo or hydrogen, with the proviso that one of R , R and R is allyloxy or allylthio; or a pharmaceutically acceptable acid addition salt thereof, a process for their...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: ROBERT MICHAEL DEMARINIS
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Compounds of the structural formula: in which: R is hydrogen or a lower alkyl of 1-6 carbons; and R , R and R are allyloxy, allylthio, halo or hydrogen, with the proviso that one of R , R and R is allyloxy or allylthio; or a pharmaceutically acceptable acid addition salt thereof, a process for their preparation and their application as alpha 2-antagonists and as intermediates for preparing alpha 2-adrenergic affinity resins.