Butenoic acids derivatives and their use in the treatment of rhinitis
The use of a compound of formula (I) in free form or in the form of a pharmaceutically acceptable salt for the preparation of a medicament for use in the treatment of rhinitis, wherein R is phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group halogen, C1-C...
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creator | KENICHIRO HOSHIKO MARC GERSPACHER |
description | The use of a compound of formula (I) in free form or in the form of a pharmaceutically acceptable salt for the preparation of a medicament for use in the treatment of rhinitis, wherein R is phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group halogen, C1-C7-alkyl, trifluoromethyl, hydroxy and C7-C7-alkoxy, R is hydrogen or C1-C7-alkyl, R is hydrogen, C1-C7-alkyl or phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group halogen, C1-C7-alkyl, trifluoromethyl, hydroxy and C1-C7-alkoxy, R is phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group halogen, C1-C7-alkyl, trifluoromethyl, hydroxy and C1-C7-alkoxy; or is naphthyl, 1H-indol-3-yl or C1-C7-alkyl-indol-3-yl, R and R are each independently of the other hydrogen or C1-C7-alkyl, at least one of R and R being hydrogen, and R is C3-C8-cycloalkyl, D-azacycloheptan-2-on-3-yl or L-azacycloheptan-2-on-3-yl. |
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or is naphthyl, 1H-indol-3-yl or C1-C7-alkyl-indol-3-yl, R and R are each independently of the other hydrogen or C1-C7-alkyl, at least one of R and R being hydrogen, and R is C3-C8-cycloalkyl, D-azacycloheptan-2-on-3-yl or L-azacycloheptan-2-on-3-yl.</description><edition>7</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2001</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20011120&DB=EPODOC&CC=AU&NR=5482501A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25546,76297</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20011120&DB=EPODOC&CC=AU&NR=5482501A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KENICHIRO HOSHIKO</creatorcontrib><creatorcontrib>MARC GERSPACHER</creatorcontrib><title>Butenoic acids derivatives and their use in the treatment of rhinitis</title><description>The use of a compound of formula (I) in free form or in the form of a pharmaceutically acceptable salt for the preparation of a medicament for use in the treatment of rhinitis, wherein R is phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group halogen, C1-C7-alkyl, trifluoromethyl, hydroxy and C7-C7-alkoxy, R is hydrogen or C1-C7-alkyl, R is hydrogen, C1-C7-alkyl or phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group halogen, C1-C7-alkyl, trifluoromethyl, hydroxy and C1-C7-alkoxy, R is phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group halogen, C1-C7-alkyl, trifluoromethyl, hydroxy and C1-C7-alkoxy; 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subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | Butenoic acids derivatives and their use in the treatment of rhinitis |
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