Butenoic acids derivatives and their use in the treatment of rhinitis

The use of a compound of formula (I) in free form or in the form of a pharmaceutically acceptable salt for the preparation of a medicament for use in the treatment of rhinitis, wherein R is phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group halogen, C1-C...

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Hauptverfasser: KENICHIRO HOSHIKO, MARC GERSPACHER
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creator KENICHIRO HOSHIKO
MARC GERSPACHER
description The use of a compound of formula (I) in free form or in the form of a pharmaceutically acceptable salt for the preparation of a medicament for use in the treatment of rhinitis, wherein R is phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group halogen, C1-C7-alkyl, trifluoromethyl, hydroxy and C7-C7-alkoxy, R is hydrogen or C1-C7-alkyl, R is hydrogen, C1-C7-alkyl or phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group halogen, C1-C7-alkyl, trifluoromethyl, hydroxy and C1-C7-alkoxy, R is phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group halogen, C1-C7-alkyl, trifluoromethyl, hydroxy and C1-C7-alkoxy; or is naphthyl, 1H-indol-3-yl or C1-C7-alkyl-indol-3-yl, R and R are each independently of the other hydrogen or C1-C7-alkyl, at least one of R and R being hydrogen, and R is C3-C8-cycloalkyl, D-azacycloheptan-2-on-3-yl or L-azacycloheptan-2-on-3-yl.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Butenoic acids derivatives and their use in the treatment of rhinitis
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