Butenoic acids derivatives and their use in the treatment of rhinitis

The use of a compound of formula (I) in free form or in the form of a pharmaceutically acceptable salt for the preparation of a medicament for use in the treatment of rhinitis, wherein R is phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group halogen, C1-C...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: KENICHIRO HOSHIKO, MARC GERSPACHER
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The use of a compound of formula (I) in free form or in the form of a pharmaceutically acceptable salt for the preparation of a medicament for use in the treatment of rhinitis, wherein R is phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group halogen, C1-C7-alkyl, trifluoromethyl, hydroxy and C7-C7-alkoxy, R is hydrogen or C1-C7-alkyl, R is hydrogen, C1-C7-alkyl or phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group halogen, C1-C7-alkyl, trifluoromethyl, hydroxy and C1-C7-alkoxy, R is phenyl that is unsubstituted or is substituted by 1, 2 or 3 substituents selected from the group halogen, C1-C7-alkyl, trifluoromethyl, hydroxy and C1-C7-alkoxy; or is naphthyl, 1H-indol-3-yl or C1-C7-alkyl-indol-3-yl, R and R are each independently of the other hydrogen or C1-C7-alkyl, at least one of R and R being hydrogen, and R is C3-C8-cycloalkyl, D-azacycloheptan-2-on-3-yl or L-azacycloheptan-2-on-3-yl.