Methods for inhibiting glucose metabolism deterioration

Methods for inhibiting glucose metabolism deterioration

The present invention provides a method of inhibiting glucose metabolism deterioration in a mammal by administering a substituted aminopyrimidine having the Formula wherein R , R , and R are, independently, hydrogen, halogen, C1-C4 alkoxy, C1-C4 alkylthio, C1-C4 alkyl, or C3-C5-cycloalky; R is hydro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: FATIMA EMITSEL YAKUBU-MADUS, MITCHELL IRVIN STEINBERG
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention provides a method of inhibiting glucose metabolism deterioration in a mammal by administering a substituted aminopyrimidine having the Formula wherein R , R , and R are, independently, hydrogen, halogen, C1-C4 alkoxy, C1-C4 alkylthio, C1-C4 alkyl, or C3-C5-cycloalky; R is hydrogen, formyl, acetyl, propionyl or butyryl; provided that R , R and R are not all hydrogen at the same time; or a pharmaceutically acceptable salt or solvate thereof.e