Sulfonamide-substituted compounds, processes for their preparation, their use as a medicament or diagnostic, and medicament comprising them

Sulphonamide-substituted compounds of formula (I) and their salts are new. X = S, SO, SO2, or CO etc.; R1, R2 = H, CF3, C2F5, C3F7, 1-6C alkyl or phenyl (optionally substituted); or R1+R2 = 2-10C alkylene; R3 = R12-CaH2aÄNR13Üm; R12 = H, 3-8C cycloalkyl, CF3, C2F5, or C3F7; a = 0-10; m = 0 or 1; R13 = H or 1-6C alkyl; or R12+R13 = 4-8C alkylene, where one of the CH2 groups may be replaced by O, S, SO, SO2, CO etc.; R4 = R14-CrH2r, where one of the CH2 groups may be replaced by O, CH=CH, C IDENTICAL C, CO, CO-O etc.; r = 1-20; R14 = H, 3-8C cycloalkyl, piperidyl, 1-pyrrolidinyl, N-morpholino, or phenyl (optionally substituted) etc.; or R3+R4 = 3-8C alkylene, one of whose CH2 groups may be replaced by O, CO, S, SO, SO2 etc.; R5+R6 = CR15=CR16-CR17=CR18, CR15=CR16-CR17=N, CR15=CR16-N=CR18, CR15=N-CR17=N, CR15=N-N=CR18, N=CR16-CR17=N or S-CR15=CR16; R15-R18 = H, F, Cl, Br, I, 1-4C alkyl, 3-8C cycloalkyl, CN, CF3 etc.; R7 = H, OH, 1-4C alkoxy, 1-4C acyloxy, Cl, Br, F or 1-4C alkyl; R8 = H or 1-6C alkyl.