ANTIHYPERTENSIVE AMINOQUINOLINES
Antihypertensive compounds for the treatment of hypertensive mammals, including man, of the formula III: III wherein X is chloro or trifluoromethyl; wherein R is a radical such as triazinyl, pyrazinyl, pyridinyl, pyrimidinyl, phenyl, or the above radicals substituted by one or two trifluoromethyl, h...
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Sprache: | eng |
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Zusammenfassung: | Antihypertensive compounds for the treatment of hypertensive mammals, including man, of the formula III: III wherein X is chloro or trifluoromethyl; wherein R is a radical such as triazinyl, pyrazinyl, pyridinyl, pyrimidinyl, phenyl, or the above radicals substituted by one or two trifluoromethyl, halo, alkyl, alkoxy, dialkylamino or alkylthio groups; or R is the group in which R1 is phenyl, phenyl substituted with one or two halo atoms, alkoxy or alkyl groups, trifluoromethyl, or R1 is alkylphenylsulfonyl; or R is the group -SO2R2, in which R2 is dialkylamino, phenyl, phenyl substituted with halo atoms, alkyl, or alkoxy groups, or trifluoromethyl are prepared from (7-chloro)- or (7-trifluoromethyl)-4-chloroquinoline or 1-[[4-[[(7-chloro)- or (7-trifluoromethyl)quinolinyl]amino]phenyl]sulfonyl]piperazine. |
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