AMIDINO-BENZYLPYRIMIDEINES

1. Amidino-benzylpyrimidines of the general formula I see diagramm : EP0000336,P9,F1 where R**1 , R**2 , and R**3 , which may be identical or different, are hydrogen, methyl, methoxy or chlorine, R**4 is alkyl of 1 to 6 carbon atoms or benzyl and R**5 and R**6 , which may be identical or different,...

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1. Verfasser: P. SCHARWAECHTER
Format: Patent
Sprache:eng
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Zusammenfassung:1. Amidino-benzylpyrimidines of the general formula I see diagramm : EP0000336,P9,F1 where R**1 , R**2 , and R**3 , which may be identical or different, are hydrogen, methyl, methoxy or chlorine, R**4 is alkyl of 1 to 6 carbon atoms or benzyl and R**5 and R**6 , which may be identical or different, are hydrogen, lower alkyl of 1 to 4 carbon atoms, trimethoxybenzyl, benzyl or phenyl, cyclohexyl, adamantyl or furfuryl, or one of the radicals R**5 and R**6 is -C6 H4 -SO2 -NH-R**7 , where R**7 is see diagramm : EP0000336,P9,F2 see diagramm : EP0000336,P9,F3 or pyrimidin-2-yl, 4-methyl-pyrimidin-2-yl, 5-methyl-pyrimidin-2-yl, 5-isopropyl-pyrimidin-2-yl, 5-methoxy-pyrimidin-2-yl, 6-methoxy-pyridazin-3-yl, 3-methoxy-pyrazin-2-yl, 5-methyl-isoxazol-3-yl or 2-pyridinyl, or R**5 and R**6 together with the nitrogen to which they are bonded are a saturated heterocyclic ring of 5-7 members, which may contain an oxygen atom or the N-Y group, where Y is methyl, benzyl or phenyl, and their pharmacologically acceptable salts with acids conventionally used for this purpose.