SOMATOSTATIN ANALOGS

Novel, therapeutically active compounds have the following formula in which Y denotes D-Val or D-Ala. The compounds can also be in the form of pharmaceutically acceptable acid addition salts. The compounds of the formula I are prepared by oxidising a corresponding tetradecapeptide, the two sulphydry...

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Bibliographische Detailangaben
Hauptverfasser:	T.M. LIN, J.E. SHIELDS
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Novel, therapeutically active compounds have the following formula in which Y denotes D-Val or D-Ala. The compounds can also be in the form of pharmaceutically acceptable acid addition salts. The compounds of the formula I are prepared by oxidising a corresponding tetradecapeptide, the two sulphydryl groups being converted into a disulphide bridge. The novel compounds can be used for inhibiting the release of growth hormones and for reducing intestinal motility.