BENZIMIDAZOLYL-2-AMINOIMIDAZOLINES

Antihypertensive pharmaceutical compositions comprising a compound of the formula (II) or pharmaceutically acceptable salts or solvates thereof wherein R1 is nitrile or amidino; R2 is hydrogen or lower hydrocarbon; R3, R4, R5 and R6 which may be the same or different, are each selected from hydrogen...

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1. Verfasser: ERIC A. WATTS
Format: Patent
Sprache:eng
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Zusammenfassung:Antihypertensive pharmaceutical compositions comprising a compound of the formula (II) or pharmaceutically acceptable salts or solvates thereof wherein R1 is nitrile or amidino; R2 is hydrogen or lower hydrocarbon; R3, R4, R5 and R6 which may be the same or different, are each selected from hydrogen, halogen, nitro, trifluoromethyl, lower alkyl, lower acyl, hydroxyl, lower etherified hydroxyl or lower acylated hydroxyl; together with a pharmaceutically acceptable carrier. The compounds of formula (II) are also useful as intermediates in the synthesis of the corresponding 2-aminoimidazoline compounds.