Synergistic combination comprising roflumilast and a pde-3 inhibitor

The PDE4 inhibitor N-(3,5-dichloropyrid-4-yl)-3-cyclopropylmethoxy-4-difluoromethoxy benzamide, a pharmacologically tolerable salt or N-oxide thereof, in combination with a PDE3 inhibitor is disclosed for use in inhibiting bronchospasms and treating acute obstructive bronchitis, asthma or COPD.

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Hauptverfasser: CHRISTIAN SCHUDT, ULRICH KILIAN DR, DIETRICH HAFNER, ARMIN HATZELMANN, ROLF BEUME, HERMANNAMSCHLER
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creator CHRISTIAN SCHUDT
ULRICH KILIAN DR
DIETRICH HAFNER
ARMIN HATZELMANN
ROLF BEUME
HERMANNAMSCHLER
description The PDE4 inhibitor N-(3,5-dichloropyrid-4-yl)-3-cyclopropylmethoxy-4-difluoromethoxy benzamide, a pharmacologically tolerable salt or N-oxide thereof, in combination with a PDE3 inhibitor is disclosed for use in inhibiting bronchospasms and treating acute obstructive bronchitis, asthma or COPD.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Synergistic combination comprising roflumilast and a pde-3 inhibitor
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