Synergistic combination comprising roflumilast and a pde-3 inhibitor

The PDE4 inhibitor N-(3,5-dichloropyrid-4-yl)-3-cyclopropylmethoxy-4-difluoromethoxy benzamide, a pharmacologically tolerable salt or N-oxide thereof, in combination with a PDE3 inhibitor is disclosed for use in inhibiting bronchospasms and treating acute obstructive bronchitis, asthma or COPD.

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Bibliographische Detailangaben
Hauptverfasser: CHRISTIAN SCHUDT, ULRICH KILIAN DR, DIETRICH HAFNER, ARMIN HATZELMANN, ROLF BEUME, HERMANNAMSCHLER
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The PDE4 inhibitor N-(3,5-dichloropyrid-4-yl)-3-cyclopropylmethoxy-4-difluoromethoxy benzamide, a pharmacologically tolerable salt or N-oxide thereof, in combination with a PDE3 inhibitor is disclosed for use in inhibiting bronchospasms and treating acute obstructive bronchitis, asthma or COPD.