Process for the fermentative preparation of clavam derivatives whereby the levels of ammonia and urea in the fermentation medium are kept low

Improved methods for the preparation of clavams by fermentation of a clavam-producing organism in a suitable medium wherein the ammonium levels are kept low so as to avoid repression of enzymes, particularly urease, are disclosed.

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Bibliographische Detailangaben
Hauptverfasser: WILLIAM HENRY HOLMS, BRIAN PETER VALENTINE, PAUL ALAN JEFFKINS, DAVID MICHAEL MOUSDALE
Format: Patent
Sprache:eng
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Zusammenfassung:Improved methods for the preparation of clavams by fermentation of a clavam-producing organism in a suitable medium wherein the ammonium levels are kept low so as to avoid repression of enzymes, particularly urease, are disclosed.