Inhibitors of serotonin reuptake

This invention provides compounds of Formula I: where A-B is -C=CH- or -CHCH2-; n is 0 or 1; R is H or C1-C4 alkyl; R is H, methyl, or ethyl; and Aryl is naphthyl or heteroaryl, each optionally monosubstituted with a substitutent selected from the group consisting of H, halo, hydroxy, C1-C4 alkyl, C...

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Bibliographische Detailangaben
Hauptverfasser:	VINCENT PATRICK ROCCO, DANIEL JAMES KOCH
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention provides compounds of Formula I: where A-B is -C=CH- or -CHCH2-; n is 0 or 1; R is H or C1-C4 alkyl; R is H, methyl, or ethyl; and Aryl is naphthyl or heteroaryl, each optionally monosubstituted with a substitutent selected from the group consisting of H, halo, hydroxy, C1-C4 alkyl, C1-C4 alkoxy, cyano, nitro, carboxamido, and trifluoromethyl; or pharmaceutically acceptable salts or hydrates thereof, provided that when n is 1, A-B is -CHCH2-; and a method for the inhibition of serotonin reuptake in mammals.