Tricyclic compounds

A compound represented by the formula (I) ÄA represents a 5- to 7-membered hydrocarbon ring group; L represents -NR -CO-, -CO-NR - and the like (R represents a hydrogen atom, a lower alkyl group, a lower acyl group and the like); M represents an alkylene linking group (a carbon atom constituting the...

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Hauptverfasser: KENJI ASAI, KOZO AOKI, FUKUICHI OHSAWA, KAZUNOBU TAKAHASHI, NOBUKAZU KAKUI, NAOMI TAKEI, YUJI TABATA, NAOYUKI NISHIKAWA, JIRO TANAKA, MAKOTO SUZUKI, MASAHARU SUGAI, AKIHIKO IKEGAWA
Format: Patent
Sprache:eng
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Zusammenfassung:A compound represented by the formula (I) ÄA represents a 5- to 7-membered hydrocarbon ring group; L represents -NR -CO-, -CO-NR - and the like (R represents a hydrogen atom, a lower alkyl group, a lower acyl group and the like); M represents an alkylene linking group (a carbon atom constituting the carbon chain may be replaced with a nitrogen atom, an oxygen atom and the like); X represents -S-, -O-, -NR -, -NR -CO- and the like (R and R represent a hydrogen atom, a lower alkyl group and the like) or a single bond; Y represents an alkyl group, an aryl group, an amino group, an aromatic heterocyclic group and the like; R represents a lower alkyl group, a lower alkenyl group, a lower alkynyl group or a lower acyl group; and R , R and R represent a hydrogen atom, a hydroxyl group, a lower alkyl group and the likeÜ or a salt thereof. The compound is useful as an active ingredient of medicaments for diseases in which neuropeptide Y is involved, ingestion control for hyperphagia and the like.