Analyte assays employing universal arrays

Analyte detection assays, as well as kits, primers and universal arrays for use in practicing the same, are provided. In many embodiments of the subject assays, a population of tagged affinity ligands is first contacted with a sample being assayed under conditions sufficient to produce binding compl...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	ALEX CHENCHIK, GRIGORIY S. TCHAGA, PETER N. SIMONENKO
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Analyte detection assays, as well as kits, primers and universal arrays for use in practicing the same, are provided. In many embodiments of the subject assays, a population of tagged affinity ligands is first contacted with a sample being assayed under conditions sufficient to produce binding complexes of tagged affinity ligand/analyte complexes between affinity ligands and their corresponding target analytes present in the sample. The resultant composition is then contacted with a universal array of tag complements under hybridization conditions and the presence of any resultant hybridized or surface bound tagged affinity ligand/analyte-tag complement structures is detected. The subject methods find use in a number of different applications, and are particularly suited for use in proteomics.