ANTIVIRAL NUCLEOSIDE ANALOGUES

Antiviral nucleoside analogues contain a substituted benzimidazole base attached to a carbocyclic ring in place of the conventional sugar residue. Particularly preferred compounds include those in which the 2-, 5- and 6- positions of the benzimidazole base are substituted by halogen. The compounds h...

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Bibliographische Detailangaben
Hauptverfasser: LEROY B TOWNSEND, JOHN CHARLES DRACH, SUSAN MARY DALUGE, MICHAEL TOLAR MARTIN, STEVEN SPENCER GOOD
Format: Patent
Sprache:eng
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Zusammenfassung:Antiviral nucleoside analogues contain a substituted benzimidazole base attached to a carbocyclic ring in place of the conventional sugar residue. Particularly preferred compounds include those in which the 2-, 5- and 6- positions of the benzimidazole base are substituted by halogen. The compounds have activity against herpes virus especially cytomegalovirus and also hepatitis B virus infections.