Vector

A autoregulatory expression vector is provided which comprises a nucleic acid sequence encoding reverse tetracycline transactivator which binds to a tet operon containing promoter in the presence of doxycycline thereby inducing expression of a protein of interest. The vector finds application in gen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	DAVID JAMES GOULD, YUTI CHERNAJOVSKY
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	A autoregulatory expression vector is provided which comprises a nucleic acid sequence encoding reverse tetracycline transactivator which binds to a tet operon containing promoter in the presence of doxycycline thereby inducing expression of a protein of interest. The vector finds application in gene therapy in the treatment of chronic conditions displaying relapsing symptoms.