Uridine-comprising therapeutic active agent for treatment of neurodegenerative disorders

Uridine is a therapeutic agent active as a growth promoter for treatment of neuron degenerative diseases deriving from pathological ageing or selective destruction, in particular uridine shows the same biological effects of NGF, when added at low doses to the culture medium, so that uridine may repl...

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Hauptverfasser: CINZIA PIAZZA, VINCENZO POLITI, MARIO +DI MATERAZZI
Format: Patent
Sprache:eng
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Zusammenfassung:Uridine is a therapeutic agent active as a growth promoter for treatment of neuron degenerative diseases deriving from pathological ageing or selective destruction, in particular uridine shows the same biological effects of NGF, when added at low doses to the culture medium, so that uridine may replace NGF as therapeutic agent in neural diseases and it may be also associated to other growth factors that allow neuron's differentiation, or with anti-cancer and anti-virus drugs that cause neuron damage. In addition uridine shows imporant trophic properties on various types of cultured cells, stimulating cell reproduction when used at rather high dose levels.