EMULSION CONTAINING PARATHYROID HORMONE FOR PERNASAL ADMINISTRATION

An emulsion for pernasal administration containing a parathyroid hormone as the active ingredient, at least one member selected among azacycloalkane derivatives represented by general formula (I), glycyrrhizic acid and nontoxic salts thereof, and a suitable amount of water. In formula (I), R represe...

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Hauptverfasser: MICHIHIKO SUGIMOTO, SEIKI MORIMOTO, HIDEO SAKAKIBARA, MASARU SAITA, YUJI SHIMOZONO, TAKAFUMI MANAKO, NAKAYUKI YAMAMOTO
Format: Patent
Sprache:eng
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Zusammenfassung:An emulsion for pernasal administration containing a parathyroid hormone as the active ingredient, at least one member selected among azacycloalkane derivatives represented by general formula (I), glycyrrhizic acid and nontoxic salts thereof, and a suitable amount of water. In formula (I), R represents alkyl, m represents an integer of 2 to 4, and n represents an integer of 1 to 15, provided that R represents C5 to C11 alkyl when n is 1 to 3. It can provide a well-absorbable and highly stable preparation.