Methods and compositions for diagnosis of hepatoma

The present invention provides methods and compositions for screening, diagnosis and prognosis of hepatoma, for monitoring the effectiveness of hepatoma treatment, and for drug development. Hepatoma-Diagnostic Features (HFs), detectable by two-dimensional electrophoresis of serum or plasma are descr...

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Bibliographische Detailangaben
Hauptverfasser: CHRISTOPHER MOYSES, PHILIP J. JOHNSON, ROBERT REID TOWNSEND, THAKORBHAI PARSHOTAMBHAI PATEL, RAJESH BHIKHU PAREKH
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention provides methods and compositions for screening, diagnosis and prognosis of hepatoma, for monitoring the effectiveness of hepatoma treatment, and for drug development. Hepatoma-Diagnostic Features (HFs), detectable by two-dimensional electrophoresis of serum or plasma are described. The invention further provides Hepatoma-Diagnostic Protein Isoforms (HPIs) detectable in serum or plasma, preparations comprising isolated HPIs, antibodies immunospecific for HPIs, and kits comprising the aforesaid.