COMPOUNDS FOR THE REDUCING LIPOTOXIC DAMAGE

Abstract Disclosed are lipase inhibitors and methods for using the same to treat inflammation, multisystem organ failure, necrotic pancreatic acinar cell death, acute pancreatitis, sepsis (e.g., culture negative sepsis), burns and acne. For example, disclosed are two lipase inhibitors useful in meth...

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Bibliographische Detailangaben
Hauptverfasser:	SINGH, Vijay P, ANANDAN, Sampath-Kumar, GREENMAN, Kevin, KAMAL, Zeeshan
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Abstract Disclosed are lipase inhibitors and methods for using the same to treat inflammation, multisystem organ failure, necrotic pancreatic acinar cell death, acute pancreatitis, sepsis (e.g., culture negative sepsis), burns and acne. For example, disclosed are two lipase inhibitors useful in methods described herein: (1) (II) or a pharmaceutically acceptable salt thereof.