METHOD FOR PRODUCING RECOMBINANT HYALURONIDASE
Disclosed is a method for producing hyaluronidase or a variant thereof. Specifically, the method is capable of changing the N-glycan levels under culture conditions including a controlled concentration of glucose in the culture medium and a decreased culture temperature for a specific culture time p...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | Nam, Ki Seok Kim, Kyuwan Park, Kibum Cho, Jeong Soo Kim, Ji-Sun Song, Hyung Nam Yun, Sang Hoon Byun, Minsoo Park, Soon-Jae |
| description | Disclosed is a method for producing hyaluronidase or a variant thereof. Specifically, the method is capable of changing the N-glycan levels under culture conditions including a controlled concentration of glucose in the culture medium and a decreased culture temperature for a specific culture time period, thereby increasing the specific activity by 10% or more and improving the quality and production yield. 300% soluble soluble variant (wild type) |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_AU2024220188A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>AU2024220188A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_AU2024220188A13</originalsourceid><addsrcrecordid>eNrjZNDzdQ3x8HdRcPMPUggI8ncJdfb0c1cIcnX293Xy9HP0C1HwiHT0CQ3y9_N0cQx25WFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8Y6hRgZGJkZGBoYWFo6GxsSpAgCLuya8</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>METHOD FOR PRODUCING RECOMBINANT HYALURONIDASE</title><source>esp@cenet</source><creator>Nam, Ki Seok ; Kim, Kyuwan ; Park, Kibum ; Cho, Jeong Soo ; Kim, Ji-Sun ; Song, Hyung Nam ; Yun, Sang Hoon ; Byun, Minsoo ; Park, Soon-Jae</creator><creatorcontrib>Nam, Ki Seok ; Kim, Kyuwan ; Park, Kibum ; Cho, Jeong Soo ; Kim, Ji-Sun ; Song, Hyung Nam ; Yun, Sang Hoon ; Byun, Minsoo ; Park, Soon-Jae</creatorcontrib><description>Disclosed is a method for producing hyaluronidase or a variant thereof. Specifically, the method is capable of changing the N-glycan levels under culture conditions including a controlled concentration of glucose in the culture medium and a decreased culture temperature for a specific culture time period, thereby increasing the specific activity by 10% or more and improving the quality and production yield. 300% soluble soluble variant (wild type)</description><language>eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241017&DB=EPODOC&CC=AU&NR=2024220188A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241017&DB=EPODOC&CC=AU&NR=2024220188A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Nam, Ki Seok</creatorcontrib><creatorcontrib>Kim, Kyuwan</creatorcontrib><creatorcontrib>Park, Kibum</creatorcontrib><creatorcontrib>Cho, Jeong Soo</creatorcontrib><creatorcontrib>Kim, Ji-Sun</creatorcontrib><creatorcontrib>Song, Hyung Nam</creatorcontrib><creatorcontrib>Yun, Sang Hoon</creatorcontrib><creatorcontrib>Byun, Minsoo</creatorcontrib><creatorcontrib>Park, Soon-Jae</creatorcontrib><title>METHOD FOR PRODUCING RECOMBINANT HYALURONIDASE</title><description>Disclosed is a method for producing hyaluronidase or a variant thereof. Specifically, the method is capable of changing the N-glycan levels under culture conditions including a controlled concentration of glucose in the culture medium and a decreased culture temperature for a specific culture time period, thereby increasing the specific activity by 10% or more and improving the quality and production yield. 300% soluble soluble variant (wild type)</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNDzdQ3x8HdRcPMPUggI8ncJdfb0c1cIcnX293Xy9HP0C1HwiHT0CQ3y9_N0cQx25WFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8Y6hRgZGJkZGBoYWFo6GxsSpAgCLuya8</recordid><startdate>20241017</startdate><enddate>20241017</enddate><creator>Nam, Ki Seok</creator><creator>Kim, Kyuwan</creator><creator>Park, Kibum</creator><creator>Cho, Jeong Soo</creator><creator>Kim, Ji-Sun</creator><creator>Song, Hyung Nam</creator><creator>Yun, Sang Hoon</creator><creator>Byun, Minsoo</creator><creator>Park, Soon-Jae</creator><scope>EVB</scope></search><sort><creationdate>20241017</creationdate><title>METHOD FOR PRODUCING RECOMBINANT HYALURONIDASE</title><author>Nam, Ki Seok ; Kim, Kyuwan ; Park, Kibum ; Cho, Jeong Soo ; Kim, Ji-Sun ; Song, Hyung Nam ; Yun, Sang Hoon ; Byun, Minsoo ; Park, Soon-Jae</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_AU2024220188A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2024</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>Nam, Ki Seok</creatorcontrib><creatorcontrib>Kim, Kyuwan</creatorcontrib><creatorcontrib>Park, Kibum</creatorcontrib><creatorcontrib>Cho, Jeong Soo</creatorcontrib><creatorcontrib>Kim, Ji-Sun</creatorcontrib><creatorcontrib>Song, Hyung Nam</creatorcontrib><creatorcontrib>Yun, Sang Hoon</creatorcontrib><creatorcontrib>Byun, Minsoo</creatorcontrib><creatorcontrib>Park, Soon-Jae</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Nam, Ki Seok</au><au>Kim, Kyuwan</au><au>Park, Kibum</au><au>Cho, Jeong Soo</au><au>Kim, Ji-Sun</au><au>Song, Hyung Nam</au><au>Yun, Sang Hoon</au><au>Byun, Minsoo</au><au>Park, Soon-Jae</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD FOR PRODUCING RECOMBINANT HYALURONIDASE</title><date>2024-10-17</date><risdate>2024</risdate><abstract>Disclosed is a method for producing hyaluronidase or a variant thereof. Specifically, the method is capable of changing the N-glycan levels under culture conditions including a controlled concentration of glucose in the culture medium and a decreased culture temperature for a specific culture time period, thereby increasing the specific activity by 10% or more and improving the quality and production yield. 300% soluble soluble variant (wild type)</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_AU2024220188A1 |
| source | esp@cenet |
| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | METHOD FOR PRODUCING RECOMBINANT HYALURONIDASE |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-14T12%3A04%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=Nam,%20Ki%20Seok&rft.date=2024-10-17&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EAU2024220188A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |