Inhibitors of the menin-MLL Interaction

Inhibitors of the menin-MLL intereaction Abstract The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL inter...

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Bibliographische Detailangaben
Hauptverfasser:	LOTESTA, Stephen D, CACATIAN, Salvacion, ZHUANG, Linghang, PARENT, Stephan D, FAN, Yi, ZHENG, Yajun, DILLARD, Lawrence Wayne, SINGH, Suresh B, DONG, Chengguo, MORALES-RAMOS, Angel, MARCUS, Andrew, JIA, Lanqi, HOUSTON, Travis L, CLAREMON, David A, VENKATRAMAN, Shankar, YUAN, Jing
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Inhibitors of the menin-MLL intereaction Abstract The present invention is directed to inhibitors of the interaction of menin with MLL and MLL fusion proteins, pharmaceutical compositions containing the same, and their use in the treatment of cancer and other diseases mediated by the menin-MLL interaction.