Orthopedic instrument connection mechanisms and related assemblies and systems

A medical device connection mechanism, related assemblies and systems comprising generally: a first medical device having: a protrusion, the protrusion including a proximal end and a distal end distally disposed from the proximal end along a height of a body of the protrusion, the body of the protrusion comprising an interrupted threaded portion disposed closer to the distal end than the proximal end; and a second medical device having: an interior sidewall, the interior sidewall defining a hole extending into the second medical device, a discontinuous threaded portion disposed within the hole, the discontinuous threaded portion defining a threadless channel extending along a discontinuous threaded portion height, and the discontinuous threaded portion configured to receive the interrupted threaded portion of the protrusion of the first medical device through the threadless channel.