Thrombosomes as an antiplatelet agent reversal agent

In some embodiments provided herein is a method of treating a coagulopathy in a subject, the method including administering to the subject in need thereof an effective amount of a composition including platelets or platelet derivatives and an incubating agent including one or more salts, a buffer, o...

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Bibliographische Detailangaben
Hauptverfasser: ISHLER, Braden Carl, LEE, Amber Nicole, MOSKOWITZ, Keith Andrew, DICKERSON, William Matthew, TANDON, Narendra Nath
Format: Patent
Sprache:eng
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Zusammenfassung:In some embodiments provided herein is a method of treating a coagulopathy in a subject, the method including administering to the subject in need thereof an effective amount of a composition including platelets or platelet derivatives and an incubating agent including one or more salts, a buffer, optionally a cryoprotectant, and optionally an organic solvent, wherein the subject has been treated or is being treated with an antiplatelet agent.